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Stan Lightfoot Selected Research

CP 31398

1/2015TP53 modulating agent, CP-31398 enhances antitumor effects of ODC inhibitor in mouse model of urinary bladder transitional cell carcinoma.
9/2013Chemopreventive effects of the p53-modulating agents CP-31398 and Prima-1 in tobacco carcinogen-induced lung tumorigenesis in A/J mice.
8/2013p53-stabilizing agent CP-31398 prevents growth and invasion of urothelial cancer of the bladder in transgenic UPII-SV40T mice.

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Stan Lightfoot Research Topics

Disease

19Neoplasms (Cancer)
11/2017 - 05/2009
12Carcinogenesis
01/2019 - 01/2008
9Adenocarcinoma
12/2015 - 09/2012
8Pancreatic Neoplasms (Pancreatic Cancer)
01/2019 - 11/2010
8Carcinoma in Situ
11/2017 - 11/2010
5Carcinoma (Carcinomatosis)
07/2014 - 11/2010
4Colonic Neoplasms (Colon Cancer)
11/2016 - 12/2013
4Transitional Cell Carcinoma
01/2016 - 08/2013
4Adenoma (Adenomas)
12/2015 - 09/2013
3Adenocarcinoma of Lung
12/2015 - 09/2013
3Lung Neoplasms (Lung Cancer)
12/2015 - 09/2013
2Inflammation (Inflammations)
06/2015 - 07/2014
2Urinary Bladder Neoplasms (Bladder Cancer)
07/2014 - 08/2013
2Kidney Neoplasms (Kidney Cancer)
08/2009 - 05/2009
1Obesity
01/2019
1Dyslipidemias (Dyslipidemia)
01/2019
1Graft vs Host Disease (Graft-Versus-Host Disease)
02/2016
1Pancreatitis
06/2015
1Fibrosis (Cirrhosis)
04/2015
1Colorectal Neoplasms (Colorectal Cancer)
03/2014
1Polyps
03/2014
1Endometrial Neoplasms (Endometrial Cancer)
03/2014
1Tuberous Sclerosis (Bourneville's Disease)
12/2013
1Diabetes Mellitus
12/2013

Drug/Important Bio-Agent (IBA)

7Pharmaceutical PreparationsIBA
11/2017 - 05/2009
5Proliferating Cell Nuclear Antigen (PCNA)IBA
12/2015 - 12/2013
3PolyaminesIBA
11/2016 - 12/2014
3Gefitinib (Iressa)FDA Link
01/2016 - 11/2010
3ErbB Receptors (EGF Receptor)IBA
10/2015 - 01/2008
3licofeloneIBA
10/2015 - 07/2014
3CP 31398IBA
01/2015 - 08/2013
3CarcinogensIBA
10/2013 - 01/2008
3(((4- nitrophenyl)amino)(2,2,4,4- tetramethyl thiochroman-6-yl)amino) methane-1-thioneIBA
08/2009 - 01/2008
2Biological ProductsIBA
01/2019 - 01/2008
2AzoxymethaneIBA
11/2016 - 12/2013
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
11/2016 - 10/2012
2Eflornithine (Ornidyl)FDA Link
11/2016 - 12/2014
2Insulin (Novolin)FDA Link
02/2016 - 03/2014
2EnzymesIBA
01/2016 - 12/2014
2Sirolimus (Rapamycin)FDA Link
01/2016 - 12/2015
2TOR Serine-Threonine KinasesIBA
12/2015 - 12/2013
24- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA
12/2015 - 09/2013
2Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
10/2015 - 06/2015
2CateninsIBA
10/2015 - 12/2013
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2014 - 08/2013
2Estrogens (Estrogen)FDA Link
03/2014 - 12/2013
2Estrogen ReceptorsIBA
03/2014 - 12/2013
2Raloxifene Hydrochloride (Evista)FDA Link
03/2014 - 12/2013
2Proteins (Proteins, Gene)FDA Link
12/2013 - 05/2009
1Protein Isoforms (Isoforms)IBA
01/2019
1LipidsIBA
01/2019
1Doublecortin-Like KinasesIBA
01/2019
1AZ10606120IBA
11/2017
13- (5- (2,3- dichlorophenyl)- 1H- tetrazol- 1- yl)methylpyridineIBA
11/2017
1Purinergic P2X7 ReceptorsIBA
11/2017
1InflammasomesIBA
11/2017
1Rosuvastatin Calcium (Crestor)FDA Link
11/2016
1PerforinIBA
11/2016
1Cyclin-Dependent Kinase Inhibitor p16IBA
05/2016
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
02/2016
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2016
1MucinsIBA
01/2016
1N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase (N-acetylglucosaminyltransferase)IBA
01/2016
1talniflumateIBA
01/2016
1NicotineFDA Link
12/2015
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
12/2015
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
10/2015
1InterleukinsIBA
10/2015
1Interleukin-22 (IL-22)IBA
10/2015
1InterferonsIBA
10/2015
1Carrier Proteins (Binding Protein)IBA
10/2015
1CeruletideIBA
06/2015
1MicroRNAs (MicroRNA)IBA
06/2015
1GlypicansIBA
04/2015
1Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA
04/2015
1HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
04/2015
1Biomarkers (Surrogate Marker)IBA
04/2015
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
04/2015
1Excipients (Suspending Agents)IBA
01/2015
1Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
12/2014
1Lipoxygenase (Lipoxygenase-1)IBA
07/2014
1Prostaglandin-E SynthasesIBA
07/2014
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
07/2014
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
03/2014
1Selective Estrogen Receptor Modulators (SERM)IBA
03/2014
1Metformin (Glucophage)FDA LinkGeneric
12/2013
1Autophagy-Related ProteinsIBA
12/2013
1Hypoglycemic Agents (Hypoglycemics)IBA
12/2013
1Adenosine Monophosphate (AMP)IBA
12/2013
1Cyclin D1IBA
12/2013
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
12/2013
1Retinoid X Receptors (Retinoid X Receptor)IBA
12/2013
1Bexarotene (LGD1069)FDA Link
12/2013
1Phosphotransferases (Kinase)IBA
12/2013
1Insulin-Like PeptidesIBA
12/2013
1Aldehyde DehydrogenaseIBA
10/2013
1SaponinsIBA
10/2013
1TriterpenesIBA
10/2013

Therapy/Procedure

6Chemoprevention
12/2014 - 01/2008
1Aftercare (After-Treatment)
05/2016